Everything about Ovarian Cyst totally explained
An
ovarian cyst is any collection of fluid, surrounded by a very thin wall, within an
ovary. Any
ovarian follicle that's larger than about two
centimeters is termed an ovarian cyst. An ovarian cyst can be as small as a
pea, or larger than a
cantaloupe.
Most ovarian cysts are functional in nature, and harmless (
benign).
(External Link
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carcinoma is approximately 15 cases per 100,000 women per year.
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Ovarian cysts affect women of all ages. They occur most often, however, during a woman's childbearing years.
Some ovarian cysts cause problems, such as bleeding and pain. Surgery may be required to remove those cysts.
Types
Functional cysts
Some, called
functional cysts, or simple cysts, are part of the normal process of
menstruation. They have nothing to do with disease, and can be treated. There are 3 types, Graafian, Luteal, and Hemorrhagic.
Graafian follicle cyst
One type of simple cyst, which is the most common type of ovarian cyst, is the
graafian follicle cyst,
follicular cyst, or
dentigerous cyst. This type can form when ovulation doesn't occur, and a follicle doesn't rupture or release its egg but instead grows until it becomes a cyst, or when a mature follicle
involutes (collapses on itself). It usually forms during ovulation, and can grow to about 2.3 inches in diameter. It is thin-walled, lined by one or more layers of
granulosa cell, and filled with clear fluid. Its rupture can create sharp, severe pain on the side of the ovary on which the cyst appears. This sharp pain (sometimes called
mittelschmerz) occurs in the middle of the
menstrual cycle, during ovulation. About a fourth of women with this type of cyst experience pain. Usually, these cysts produce no symptoms and disappear by themselves within a few months.
Ultrasound is the primary tool used to document the follicular cyst. A pelvic exam will also aid in the diagnosis if the cyst is large enough to be seen. A doctor monitors these to make sure they disappear, and looks at treatment options if they do not.
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Corpus luteum cyst
Another is a
corpus luteum cyst (which may rupture about the time of
menstruation, and take up to three months to disappear entirely). This type of functional cyst occurs after an egg has been released from a follicle. The follicle then becomes a secretory gland that's known as the
corpus luteum. The ruptured follicle begins producing large quantities of
estrogen and
progesterone in preparation for conception. If a pregnancy doesn't occur, the corpus luteum usually breaks down and disappears. It may, however, fill with fluid or blood, causing the corpus luteum to expand into a cyst, and stay on the ovary. Usually, this cyst is on only one side, and doesn't produce any symptoms.
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clomiphene citrate (
Clomid, Serophene), used to induce
ovulation, increases the risk of a corpus luteum cyst developing after ovulation. These cysts don't prevent or threaten a resulting pregnancy.
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Hemorrhagic cyst
A third type of functional cyst, which is common, is a
Hemorrhagic cyst, which is also called a blood cyst,
hematocele, and hematocyst.
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sonogram.
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) Occasionally hemorrhagic cysts can rupture, with blood entering the abdominal cavity. No blood is seen out of the vagina. If a cyst ruptures, it's usually very painful. Hemorrhagic cysts that rupture are less common. Most hemorrhagic cysts are self-limiting; some need surgical intervention. Even if a hemorrhagic cyst ruptures, in many cases it resolves without surgery. Patients who don't require surgery will experience pain for 4 - 10 days after, and may require several days rest. Studies have found that women on tetracycline antibiotics recover 25% earlier than the majority of patients, a surprising correlation found in 2004. Sometimes surgery is necessary,
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laparoscopy ("belly-button surgery" that uses small tools inserted through one or more tiny slits in the abdomen).
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Dermoid cyst
Endometrioid cyst
An
endometrioma,
endometrioid cyst,
endometrial cyst, or
chocolate cyst is caused by
endometriosis, and formed when a tiny patch of endometrial tissue (the
mucous membrane that makes up the inner layer of the uterine wall) bleeds, sloughs off, becomes transplanted, and grows and enlarges inside the ovaries. As the blood builds up over months and years, it turns brown. When it ruptures, the material spills over into the pelvis and onto the surface of the uterus, bladder, bowel, and the corresponding spaces between. Treatment for endometriosis can be medical or surgical.
Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently used first in patients with pelvic pain, particularly if the diagnosis of endometriosis hasn't been definitively established. The goal of directed medical treatment is to achieve an
anovulatory state. Typically, this is achieved initially using
hormonal contraception. This can also be accomplished with progestational agents (for example,
medroxyprogesterone),
danazol,
gestrinone, or
gonadotropin-releasing hormone agonists (
GnRH), as well as other less well-known agents. These agents are generally used if oral contraceptives and NSAIDs are ineffective. GnRH can be combined with
estrogen and
progestogen (add-back therapy) without loss of efficacy but with fewer hypo
estrogenic symptoms. Laparoscopic surgical approaches include
ablation of implants,
lysis of adhesions, removal of endometriomas, utero
sacral nerve ablation, and presacral
neurectomy. They frequently require surgical removal. Conservative surgery can be performed to preserve fertility in young patients. Laparoscopic surgery provides pain relief and improved fertility over diagnostic laparoscopy without surgery. Definitive surgery is a
hysterectomy and
bilateral oophorectomy.
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Pathological cysts
Other cysts are
pathological, such as those found in
polycystic ovary syndrome, or those associated with
tumors.
A polycystic-appearing ovary is diagnosed based on its enlarged size — usually twice normal —with small cysts present around the outside of the ovary. It can be found in "normal" women, and in women with endocrine disorders. An
ultrasound is used to view the ovary in diagnosing the condition. Polycystic-appearing ovary is different from the polycystic ovarian syndrome, which includes other symptoms in addition to the presence of ovarian cysts, and involves metabolic and cardiovascular risks linked to insulin resistance. These risks include increased
glucose tolerance,
type 2 diabetes, and
high blood pressure. Polycystic ovarian syndrome is associated with
infertility, abnormal bleeding, increased incidences of pregnancy loss, and pregnancy-related complications. Polycystic ovarian syndrome is extremely common, is thought to occur in 4-7% of women of reproductive age, and is associated with an increased risk for endometrial cancer. More tests than an ultrasound alone are required to diagnose polycystic ovarian syndrome.
Symptoms
Some or all of the following symptoms may be present, though it's possible not to experience any symptoms:
- Dull aching, or severe, sudden, and sharp pain or discomfort in the lower abdomen (one or both sides), pelvis, vagina, lower back, or thighs; pain may be constant or intermittent -- this is the most common symptom
- Fullness, heaviness, pressure, swelling, or bloating in the abdomen
- Breast tenderness
- Pain during or shortly after beginning or end of menstrual period.
- Irregular periods, or abnormal uterine bleeding or spotting
- Change in frequency or ease of urination (such as inability to fully empty the bladder), or difficulty with bowel movements due to pressure on adjacent pelvic anatomy
- Weight gain
- Nausea or vomiting
- Fatigue
- Infertility
- Increased level of hair growth
- Increased facial hair or body hair
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Treatment
About 95% of ovarian cysts are
benign, meaning they're not cancerous.
Treatment for cysts depends on the size of the cyst and symptoms. For small, asymptomatic cysts, the wait and see approach with regular check-ups will most likely be recommended.
Pain caused by ovarian cysts may be treated with:
pain relievers, including nonsteroidal anti-inflammatory drugs such as ibuprofen (Motrin, Advil), acetaminophen (Tylenol), or narcotic pain medicine (by prescription) may help reduce pelvic pain.(External Link
) NSAIDs usually work best when taken at the first signs of the pain.
a warm bath, or heating pad, or hot water bottle applied to the lower abdomen near the ovaries can relax tense muscles and relieve cramping, lessen discomfort, and stimulate circulation and healing in the ovaries.(External Link
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chamomile herbal tea (Matricaria recutita) can reduce ovarian cyst pain and soothe tense muscles.(External Link
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urinating as soon as the urge presents itself.(External Link
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avoiding constipation, which doesn't cause ovarian cysts but may further increase pelvic discomfort.(External Link
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in diet, eliminating caffeine and alcohol, reducing sugars, increasing foods rich in vitamin A and carotenoids (for example, carrots, tomatoes, and salad greens) and B vitamins (for example, whole grains).(External Link
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combined methods of hormonal contraception such as the combined oral contraceptive pill -- the hormones in the pills may regulate the menstrual cycle, prevent the formation of follicles that can turn into cysts, and possibly shrink an existing cyst. (American College of Obstetricians and Gynecologists, 1999c; Mayo Clinic, 2002e)(External Link
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Also, limiting strenuous activity may reduce the risk of cyst rupture or torsion.
Cysts that persist beyond two or three menstrual cycles, or occur in post-menopausal women, may indicate more serious disease and should be investigated through ultrasonography and laparoscopy, especially in cases where family members have had ovarian cancer. Such cysts may require surgical biopsy. Additionally, a blood test may be taken before surgery to check for elevated CA-125, a tumor marker, which is often found in increased levels in ovarian cancer, although it can also be elevated by other conditions resulting in a large number of false positives.
For more serious cases where cysts are large and persisting, doctors may suggest surgery. Some surgeries can be performed to successfully remove the cyst(s) without hurting the ovaries, while others may require removal of one or both ovaries.(External Link
)Further Information
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